Folic Acid & L-5-MTHFR

Folic Acid & L-5-MTHFR

THE DIFFERENCE BETWEEN FOLIC ACID AND L-5-MTHF. What’s the difference between folate and folic acid? Folate is a generalized term for a group of water soluble b-vitamins, and is also known as B9. Folic acid refers to the oxidized synthetic pharmaceutical that is added to processed foods and dietary supplements for “food fortification”. Folate refers to any variety of tetrahydrofolate derivatives naturally found in food. Science has well established that adequate folate intake from the consumption of folate-rich foods is essential for health. Folate aids the complete development of red blood cells, reduces levels of homocysteine in the blood, and supports proper nervous system development and function. Tetrahydrofolate (THF) is the useable form of folate the cells need for their functions.   Natural folates, found in foods, are utilized in the small intestine.  Folic acid must undergo initial reduction and methylation in the liver, and then converted to the THF form; this requires a specific enzyme absent or impaired in up to 60% of the population. The...
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The difference between MethylFolate and Folic acid

But wait! My doctor says Folic acid is important to take!! Conventional Doctors often use the terms ‘folic acid’ and ‘folate’ interchangeably. However they are not interchangeable. Folic acid refers to the oxidized synthetic pharmaceutical that is added to processed foods and dietary supplements for “food fortification”. Folic acid is synthetic compound manufactured in a laboratory where folate is the naturally occurring, and the body does not utilize them the same. Human exposure to folic acid was non-existent until its chemical synthesis in 1943. Upon the addition of synthetic folic acid to food by government mandate in 1989, the US has seen a rise in autism, infertility, autoimmune disease and cancers. With a high intake of folic acid in a standard American diet, un-metabolized folic acid could mask a vitamin B12 deficiency which can harm central nervous system function. Taking high doses of synthetic folic acid with a MTHFR mutation blocks the ability to absorb and assimilate natural folate and methylfolate; THIS...
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MTHFR & Male Fertility

MTHFR & Male Fertility

Daddy’s Genes Matter!! So much of the focus on Fertility and MTHFR falls on the mother and her genetic contribution. However 50% of the baby’s genome comes from DAD! We evaluate and scrutinize mom’s diet and yet dad is left alone! Recently powerful new research on MTHFR mutations and miscarriages implicates the fathers role more than we thought possible. While each parent contributes equal DNA to their offspring, it is women, mothers that come to office visits and comply with recommendations. Next time ladies! Bring your man! A recent large scale study proved correlation that BOTH the MTHFR C677T and the A1298C contributed from BOTH parents increased risk of miscarriage. Interestingly, babies with 2 copies of the MTHFR A1298c mutation had the highest incidence of miscarriage. 2 copies of a mutation means EACH parent donated one copy! DAD’s Genes matter too! So here at the FWC our preconception health protocol includes BOTH parents! And the “inception” of the protocol is months before “conception”. A...
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MTHFR..an introduction

MTHFR..an introduction

Faulty methylation has been linked to heart disease, stroke, reproductive disorders, neurodegenerative diseases like Alzheimer's, Parkinson’s, ADHD, Autism Spectrum Disorders and fertility issues. It has also been linked to chronic fatigue, anxiety, depression, colon cancer, reproductive cancers, kidney infarct, cervical dysplasia, faulty detoxification and impaired DNA repair. Methylation occurs when SAMe (S-adenosine methionine) donates a methyl group, which is then attached to the molecule that is being detoxified. SAMe then becomes homocysteine. Vitamin B6, B12, and folate are necessary to reduce homocysteine and keep the methylation process occurring smoothly. Methylation is also used in DNA regulation. If you have poor methylation, your cells will not function correctly leading to decline in health. • MTHFR (Methylenetetrahydrofolate reductase) It is first converted to tetrahydrofolate (THF) then to 5,10-methyleneTHF. MTHFR is needed to further convert 5,10-methyleneTHF into active 5-methylTHF, in order to convert methionine from homocysteine. • MTR - 5-methyltetrahydrofolate-homocysteine methyltransferase is encoded by the MTR gene. It’s task is to regenerate methionine from homocysteine by using 5-Methyl-THF(levomefolic...
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MTHFR and Chiropractic

MTHFR and Chiropractic

  Recently there has been a lot of talk about MTHFR (methylenetetrahydrofolate reductase gene that contains the DNA code to produce the MTHFR enzyme. This enzyme, simply stated, helps us convert B vitamins into energy inside the cells) When there are mutations or variations in the MTHFR gene, there is enzymatic malfunction or decreased function, this is implicated in everything from serious genetic disorders to no so serious nuisance type problems. Because MTHFR is genetic, and appears in 60% of the population, there is little we can do about what passes to us from our parents, but a host of things we can do to support functioning of this enzyme and support the proper energy production. Many factors related to MTHFR, can cause a person to become deficient in vitamins, minerals, amino acids and antioxidants; and conversely have higher levels of inflammation. So the standard clean diet, good sleep, exercise and of course chiropractic apply here..however chiropractic can also be a useful tool...
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