Warrior or Worrier? The truth about COMT

Warrior or Worrier? The truth about COMT

  Catechol-O-methyltransferase (COMT) is one of several enzymes that degrade catecholamines such as dopamine, epinephrine, and norepinephrine. In humans, catechol-O-methyltransferase protein is encoded by the COMT gene. COMT is mostly found in the peripheral nervous system, and less significantly found in the Central Nervous System, and found in the highest concentration in the liver.   There are 2 types of COMT expression, the warrior and the worrier.   Warrior Generally have a higher IQ do better on tests better toxin elimination higher estrogen elimination higher incidence of ADHD Higher pain tolerance Normal magnesium levels Normalized B12 and folate levels Even tempered Worrier Slower estrogen elimination and estrogen dominance Lower pain tolerance Increased probability of addiction and anorexia PMS worse in females Enhanced response to stimulants Red face after exercise & Decreased Sweating Lower Mg levels Lower Intracellular b12 and folate Prone to mood swings and mania               COMT is the enzyme that allows you to spare the “feel good hormones” dopamine and nor-epinephrine. If this enzyme is completely blocked mood swings and addiction can occur. Keeping the gut healthy with probiotics and a good diet assures proper conversion of...
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