Extra Chromosome & Absent Enzyme; A look at Down Syndrome and MTHFR

Down Syndrome is a genetic mutation identified by an extra 21st chromosome. MTHFR is a genetic mutation identified by the absence of a vital enzyme essential for folate metabolism. There is an intimate connection between these 2 conditions, and by identifying MTHFR in children with Down Syndrome risks for many co-morbid conditions can be reduced or eliminated. Contributing Factors • Environmental and Maternal Disposition. There has been recent research showing there is a higher incidence of children with Down syndrome born to mothers that are positive for MTHFR. Multiple polymorphisms were identified in this study which simply correlates the association. Practically speaking MTHFR mutations are seen in elevated levels in autism, spina bifida, fetal cardiac defects and Down syndrome. However, to solely implicate genetics in any medical condition is bad medicine. The environment plays such a large role in influencing our genes. Because of the role that MTHFR plays in folate metabolism and Homocysteine metabolism this association bears regard and acknowledgement. It has been...
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Bedwetting and B12

Bedwetting and B12

Bedwetting We all diaper and clean our babies, and then at some point, almost like a switch, we decide this is no longer acceptable. “Potty Training” begins and there is a billion dollar industry that boasts “simple” and ‘quick” ways to facilitate this process. Let’s review how we got to this point…. We diaper newborns because their nervous system is not yet fully developed. As these little beings grow, we feed them nutrient dense breast milk and foods to develop a properly functioning nervous system.  As children continue to grow and develop, the frequency of nighttime wetting decreases and continence improves. Yet some children continue bedwetting while others stop. Methylation and bedwetting As with many facets of development, there are numerous reasons why a single condition, such as nighttime wetting, can have multiple contributing causes. The bulk of cases are more stubborn than the amelioration by common sense remedies such as reducing or eliminating sugar, urination just before bedtime, elimination of caffeine, and removing or reducing electronics...
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